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Why do some patients experience remarkable responses to immunotherapy while others don’t?
This has become one of the defining questions in cancer research. Part of the answer may lie in something researchers describe as "hot" and "cold" tumors.
Over the past few years, the concept of hot and cold tumors has helped researchers understand why some tumors respond to immunotherapy while others do not.
Today, scientists are taking this one step further by examining the specific immune cells and biological pathways within the tumor microenvironment that drive treatment response or resistance.
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