Dissertations still flying out:
Clever-1 inhibition in human cancer: consequences and control of bexmarilimab-induced macrophage activation
Doesn’t look too bad, at least in a layman’s eyes. Big money will decide sometime in the future what it’s worth!
Edit: Translation of the summary:
Altogether, these results pave the way for the clinical development of bexmarilimab treatment by determining preliminary efficacy, immune correlates of bexmarilimab response, and potential markers for patients likely to respond to treatment. In the future, controlled clinical trials can formally measure the efficacy of treatment, validate the best patient selection methods, and investigate presumed treatment combinations to improve effectiveness. Further studies focusing on non-immune cell types of the TME, especially cancer and endothelial cells, will further deepen the understanding of the effects of bexmarilimab treatment in tumors.