DermTech - Revolutionizing Skin Lesion Examination

Let’s open a thread for DermTech, which immediately caught my eye when it appeared on Twitter.

$DMTK - DermTech - by Jonah Lupton ← Jonah Lupton’s thoughts, from which I shamelessly build the foundation for this thread.

The company was founded in 1995, and went public in 2019 with the ticker $DMTK. Its headquarters are in California and it currently operates in the US market. I’ll copy a good summary in English from Jonah Lupton’s email here (I recommend following him on Twitter).

At the time of creating this thread:
Stock price $43
Market cap 1.86 billion
P/E and other metrics, better not to look.

"DermTech ($DMTK) is a molecular diagnostics company that develops and markets non-invasive diagnostic tests to diagnose skin cancer and other skin related conditions. The company offers Pigmented Lesion Assay (PLA), a gene expression test that helps rule out melanoma and the need for a surgical biopsy. $DMTK also provides the Nevome test, an adjunctive reflex test for the PLA and adhesive skin sample collection kits, as well as gene expression assays for the Th1, Th2, IFN-gamma, and Th17 inflammatory pathways. $DMTK is also developing non-melanoma skin cancer diagnostic and non-melanoma skin cancer risk assessment products. The $DMTK Melanoma Test is a new kind of lab test that looks for signs of melanoma in your skin’s genomic material. "

Here’s about the revenue:

  • 2019 revenues: $3 million
  • 2020 revenues (est): $6 million
  • 2021 revenues (est): $12 million

2020 Q3 results

https://investors.dermtech.com/news-releases/news-release-details/dermtech-reports-third-quarter-2020-financial-results

So, in practice, the current operating model is suspicious skin lesion → doctor’s assessment → possible monitoring or surgery and pathology.

DermTech’s test is simply rubbed on the skin lesion with several patches, and these are sent to DermTech’s own laboratory where they are analyzed (RNA analysis with a “gene expression” test). This is a completely painless method and leaves no scar, unlike surgery.

With this test, melanoma, for example, is detected much earlier than with traditional examination methods, it is cheaper, and the results are more accurate. Dermtech’s accuracy is 99% vs. the current treatment pathway’s 83% accuracy.
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“Cancer starts when genes mutate within a cell. This altered cell duplicates and duplicates until enough cells exist to be seen under a microscope (and then, eventually, even without one). $DMTK’s genomic analysis can find these altered cancerous cells long before they show up under a microscope, through a proprietary gene expression test.”

The product is primarily aimed at use by doctors, but now, due to COVID, an opportunity has also arisen to sell kits directly to consumers, who then mail the samples to DermTech’s lab.

Regarding market potential, Dermtech estimates their current and future product pipeline to be worth approximately a 10 billion dollar market.


Now that Dermtech has a developed and approved product, the next challenge is to build a strong sales team to aggressively push the product into the market. Due to COVID, there have been many challenges in marketing the product, as most non-urgent doctor visits and clinics have been closed. Recruitment has been intense, and the team is starting to come together.

The valuation is tight, but Jonah Lupton’s comments describe the situation well:
"The current financials and revenue forecasts for $DMTK are nothing to get too excited about because we’re still dealing with small numbers compared to more established companies in the healthcare industry.

However I believe $DMTK could grow revenues at 100% per year for the next 3-5 years (maybe longer). I have spoken to several dermatologists over the past couple weeks and they all said that $DMTK’s new smart patch is an absolute game changer for them and their patients.

Based on $DMTK’s December 2020 estimate of 2,900 billable samples processed the 2021 revenue estimates of $12 million will end up being way too low if the company continues on this same run rate however given the number of new sales reps it’s likely this monthly sample processing number continues to increase as well."

Insiders also have skin in the game.

Marketscreener currently shows 3 analysts following the company, with a consensus target price of $52. All recommend buying.

Dermtech recently arranged a 140 million share offering, so it’s unlikely a new offering is coming soon. But I assume one will still rumble, as I have no information about profitability at this stage.

All in all, I became really interested in Dermtech and will probably open a position once I delve deeper into the company tomorrow. In the meantime, I thought I’d open a forum for Inderes as well, to gather other interested people and exchange ideas and research the company further.
Easier, safer, cheaper why wouldn’t it work and revolutionize the examination of skin lesions?

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Thanks for starting this thread, I also found it through Lupton. Interesting company that deserves more attention.

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During my previous profession, I was involved in just under a hundred mole removals. Even then, I wondered if there wasn’t an easier way. Often, customers have a “barrier” to getting moles checked solely due to the difficulty of the process. Also, one step could be completely eliminated from the treatment pathway. Currently, we have a nurse-doctor-removal appointment process. With this process, it could be shortened to a nurse performing this test, after which further steps are decided.

In the future, I see this type of company as a pretty clear acquisition target for larger ones.

Here are Dermtech’s patents:

And indeed, when considering the market, skin cancers are a sadly growing subtype of cancer.

Generally, skin cancers are considered a disease of those over 65, but unfortunately, statistics are starting to look bad for young people too.

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I’ve had that operation myself once, and that’s also why I got interested - this would be an obvious better alternative.

In addition to shortening the treatment path, the operation itself required both a doctor and a nurse to be present, meaning the work of two people. In my case, it took quite a long time for the health center to find a time when both were available - and waiting is not pleasant anymore when your own threshold with cancer concern has progressed to the point where you’ve obtained a referral for examination.

Based on this, my first impression is that this is an all-around sensible solution for both the patient and the system, saving resources.

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Craig-hallum comments as he raised TP to $49

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Thanks to the starter for educating me. I’ve been following Scibase Holding’s world conquest with Nevisense, which is based on skin’s electrical conductivity and AI-based data analysis. With its disposable sensors, it gave me strong Icare-Revenio vibes. This DermTech now, after a long time, seems like a viable diagnostic method for melanoma in addition to Nevisense.

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original (1).pdf (2.0 MB)

Here’s DermTech’s Q4 2020 investor presentation.
I recommend reading through it. It also mentions pent-up demand due to the coronavirus, which will be released in 2021-2022.
This case still has an Ark Investment option for this year. If they get involved and add it to their portfolio, the company tends to get on the radar of more investors.

This slide is particularly important in my opinion.

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Thanks for the intro, I joined in with a small position. It looks promising, as I work in the industry and believe in this product. In recent years, I’ve had seven moles removed (and I’m under 35), all of which were diagnosed with basal-cell carcinoma. This product would make the whole process easier, both for me as a patient and for the HCP.

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DermTech is now open for trading at Osuuspankki as well :+1:

This sounds exactly like what I’ve started looking for in my portfolio: early-stage, small health tech targets, high-risk, high-return investments. I’ll put a tiny sum into this one too and let it grow among the others. They’ve probably exaggerated a bit about their products in their own presentations, but cheaper, more accurate, faster, and less painful still sounds good, even if it brings expectations down to earth a bit.

I read their instructions on how to do the test at home, and even I understood it on the first read. It can’t be a very complicated process.

The video provides a more detailed description of Dermtech’s product. It clarifies, for example, that with this patch, a person can even take a skin sample themselves and send it to a doctor/lab. Now I am even more convinced about this product.

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I’ll answer with my own thoughts on the company.

First of all,

I somehow incomprehensibly rushed with the stock price of this share and managed to take a loss of a few hundred in the middle of a price increase… it still stings, because I thought and still think Dermtech’s product is very good. I think I wanted to put the money into Gamestop…

But to the point: I researched a few competing companies before making an investment decision, and I didn’t find any comparable to Dermtech. Scibase, mentioned in this thread, seems “so last season” compared to this. Scibase’s method is certainly a better option than visual assessment, but it still requires equipment.

It’s easy to come up with several advantages for the patch method against equipment. Cost savings and efficiency come to mind first. It’s also significantly easier for both the patient and the doctor/laboratory technician.

Skinvision, on the other hand, is a company whose application allows the user (patient) to take a picture of their mole with a mobile phone and send it to a doctor for evaluation. No comparison with Dermtech.

If someone wants to research these competitors, I looked at names from this page: https://swingtradebot.com/stocks-tagged-as/6265-melanoma

I might re-enter, but I think I made a pact with myself that I wouldn’t venture into unknown waters anymore. Not even if I FOMO.

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AH +29% with this news…

https://finance.yahoo.com/news/dermtech-enters-agreement-blue-cross-210100658.html

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Blue Cross is an insurance company in the US. For this case, it is therefore extremely important that DermTech’s products are covered by insurance so that their use can be as widespread as possible. This agreement also brought in 6 million more potential patients.

And it also adds to the credibility of the case when big health insurance companies start covering DermTech’s products :slight_smile:

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I’d say that in the long run, the credibility of the diagnosis is much more important than those 6 million potential customers. The threshold for others to get involved decreases. After this news, I got the same feeling as I did with Revenio back when I bought it. Missed purchases bother me more than bad ones, so I just have to add more shares after this.

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Lake Street raised the price target to $79 and maintains a Buy rating.

“In addition, Flaten said an investor call with a dermatologist who began using DermTech’s PLA in the middle of last year “confirmed our underlying investment thesis””

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https://twitter.com/JonahLupton/status/1365342016213819392?s=19

Popcorn ready :slight_smile: :popcorn:

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I was just looking at Dermtech’s open positions to pass the time. 24 positions open right now.

One of the positions Director Investor Relations at DermTech

I’ll have to keep an eye on whether the positions get filled.

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